On 12 August 1992, the National Science Museum Thailand or NSM was founded to commemorate the Fifth Anniversary of Her Majesty Queen Sirikit The Queen Mother’s Birthday and her leadership in integrating science, technology, Thai art and culture to develop and improve careers and the quality of life of the Thai people. The museum construction began in 1994. In the Royal Decree of Establishing the NSM, it is a state enterprise since 30 January 1995 to be under the Ministry of Science and Technology at that time, now called the Ministry of Higher Education, Science, Research and Innovation.
The National Science Museum, Thailand started to develop its first museum, “The Science Museum”, located at Technopolis, 39 Moo 3 Khlong 5, Khlong Luang, Pathum Thani. With the unique structure represents a grouping of three huge cubes standing on their points joined along the edges, forming the most spectacular building in the complex. It consists of a 10,000 square meter area with 6 major themed exhibition areas and displaying hands-on models about basic science, science and technology in everyday life, and traditional Thai technology. The Science Museum is public opened on 9 June 2000.